Active Studies Finder

Overview

Are you interested in taking part in a research study that aims to reduce anxiety in older people with chronic worry? 

The purpose of this trial is to see if a new form of talking therapy called Acceptance and Commitment Therapy plus usual care can reduce anxiety in older people with chronic worry that has not improved after previous treatment compared to usual care alone.

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Overview

We want to find out if behavioural activation (BA) works for young people with low mood. There are a lot of keen therapists in Child and Adolescent Mental Health Services (CAMHS) who would like to give better help to young people but need more training. We would like to give these therapists training in our BA. We also want to find out if our BA is good value for money, how easy it is to use for young people, carers and clinicians, and if it can reduce long waits for other therapy.

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Overview

CONNECT is a study using digital technology to see if we can detect in advance if someone’s mental health might be getting worse.

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Overview

This study is no longer looking for new participants but is still ongoing. 

This study aims to find out how Alcohol Assertive Outreach Teams (AAOT) services were first set up and how well they run. For this purpose, two experienced researchers will interview service users, staff, and other key people about their experiences with AAOT. 

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Overview

We want to find out if parents with psychosis are happy to use a self-help parenting programme, and if they find it helpful and easy to use. 

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Overview

RAPID is a study using online and phone-based psychological support to help prevent psychiatric hospital admissions for those with suicidal thoughts. The RAPID trial aims to compare two remote interventions with the standard care people usually receive to find out how best to help those who experience suicidal thoughts, and if this can reduce admissions to hospital.

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Overview

The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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We want to explore if matching certain subgroups of people with depression to a particular therapy would help patients.  In this pilot randomized controlled trial, we will randomly assign some Talking Therapies sites to an experimental group, and others to a control group.  The TherapyMatch-D computer programme will give a personalised treatment recommendation to some patients in the experimental group. 

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Overview

The study aims to assess the effectiveness of NHS and independent sector inpatient mental health rehabilitation services.

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Overview

This study is no longer looking for new participants but is still ongoing.

Culturally-adapted Family Intervention (CaFI) is a talking therapy designed together with Black service users, their families and community members for people from African-Caribbean backgrounds experiencing psychosis.

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Overview

This study is no longer looking for new participants but is still ongoing.

DAWN-P is a study to help identify postnatal depression in new parents through the use of smartphone app. 

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Overview

This study is no longer looking for new participants but is still ongoing.

This study is looking at ways of improving therapies so they are better at supporting people who self-harm. 

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Overview

This research project aims to improve long-term benefits for patients that have received low intensity treatment for depression and/or anxiety in Improving Access to Psychological Therapies (IAPT) services. 

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Overview

This study is no longer looking for new participants but is still ongoing.

This research study is investigating troriluzole (BHV-4157) in participants with Obsessive Compulsive Disorder (OCD). A further study is aking place to evaluate how safe and well tolerated troriluzole is when administered as a single dse of 280mg over a long period of time. 

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The Community Mental Health Team is taking part in a research study to evaluate how compassion can help with your wellbeing and bonding with your baby.

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This study investigates which combinations of support and therapies are helpful for different people experiencing psychosis in order to improve services. 

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This study is no longer looking for new participants but is still ongoing.

The STAR trial is for people who have been through stressful or traumatic events that have had a lasting impact on them and have problems such as hearing, seeing or feeling things that others can’t, or who have worries about harm or persecution.

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Overview

This study is no longer looking for new participants but is still ongoing.

Combining stop smoking support with online mental health treatment via SilverCloud+.

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Overview

We have developed the PROSPECT programme for people in prison who may be at risk of suicide. The aim of the programme is to help prevent suicide in prisons. We are currently conducting research to find out if the PROSPECT programme is effective. 

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Overview

The purpose of this study is to gather information about self-harm in prison and to understand your views on interventions (treatments or help) that may be helpful. The aim is to help develop future interventions for men who self-harm in prison.

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Overview

This study is no longer looking for new participants but is still ongoing.

The CELIA clinical trial is researching a potential treatment for people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia by focusing on a protein called tau. Abnormal tangles of built-up tau protein can be considered a key sign of the disease. We want to understand if different doses of a study medication called BIIB080 could be safe and have an effect on the progression of Alzheimer’s disease.

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Overview

This study aims to find out whether an antidepressant medication (sertraline) can reduce the risk of depression happening at all after first-episode psychosis (FEP), and whether preventing depression can improve recovery.

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We are looking for healthy volunteers, people with memory problems, people with movement disorders and stroke survivors to help us with a new research study. 

This study is developing a new computer program to help improve the quality of care for people who may be experiencing changes to their thinking and memory

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Overview

The reason for this research is that we do not know what is the optimum time that people should remain in Early Intervention services. This study is part of a larger programme of work which will help the research team make suggestions for the optimum time for the duration of Early Intervention services. 

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We aim to help scientists and doctors understand how hearing and Alzheimer's disease (AD) are linked.

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Overview

This research study which aims to reach agreement on key priorities for a service user-centred care model to be run alongside current NHS services for people at risk of developing psychosis (often called ‘ARMS’ [At-Risk Mental State] or ‘EDIT’ [Early Detection and Intervention Team]) through voting for preferences using surveys.

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Overview

We are currently conducting the VENTURA-RWE clinical research study for adults with major depressive disorder (MDD). This is an observational study of disease characteristics and real-life standard of care effectiveness in patients who have MDD with anhedonia and an inadequate response to antidepressant therapy, including an SSRI or SNRI. 

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Overview

We are looking for volunteers with Mild Cognitive Impairment (MCI) and/or somebody close to them to take part in surveys and interviews to find out what is important to them. This will help with future research aiming to improve the lives of people with MCI.

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Overview

This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

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Overview

The purpose of this study is to see if genetic testing could be useful for patients who are currently taking or due to start taking an antidepressant, antipsychotic or mood stabilising medicine as treatment for a mental illness. We also seek to understand how genetic and environmental factors may lead to the onset of mental health problems.

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