About GMDRC

The Greater Manchester Dementia Research Centre (GMDRC) has a 10-year track record of connecting people living with dementia with cutting-edge studies run by industry partners or the National Institute for Health Research (NIHR). We have close links to the University of Manchester through the Faculty of Biology, Medicine and Health and the Geoffrey Jefferson Brain Research Centre (GJBRC).

Locally, with our GM partners, the Manchester Clinical Research Facility and Health Innovation Manchester, we provide the infrastructure and expertise necessary to bring disease-modyfing medications to Greater Manchester.  Together with patients and partners our aim is to be part of a global team that brings the first disease-modifying medications to patients living with dementia. 

We use the state-of-the-art PET-MRI scanner located in St. Mary's Hospital and funded by the Dementias Platform UK to examine the earliest parts of the brain affected by Alzheimer's and other dementias. Nationally, working with the UK Brain Health Network (Bristol, Edinburgh, London, Cambridge, Oxford, Manchester, Newport and Belfast) we aim to bring molecular diagnostics into routine practice in the UK.

Dr Ross Dunne

Unit Director: Dr Ross Dunne

Later Life Psychiatrist and Dementia Research Specialist, GMMH

  • The CELIA clinical trial

    The CELIA clinical trial is researching a potential treatment for people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia by focusing on a protein called tau. Abnormal tangles of built-up tau protein can be considered a key sign of the disease. We want to understand if different doses of a study medication called BIIB080 could be safe and have an effect on the progression of Alzheimer’s disease.

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  • The CognoSpeak study

    CognoSpeak are looking for healthy volunteers, people with memory problems, people with movement disorders and stroke survivors to help with a new research study. This study is developing a new computer program to help improve the quality of care for people who may be experiencing changes to their thinking and memory.

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  • The StrataStem study

    The aim of the study is to create new neurons (brain cells). This will then allow us to study the genes involved in dementia. The overall aim of the research is to help us understand the biology behind Alzheimer’s disease and, potentially, identify new drugs to treat the disease.

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